CBG vs. CBC: Comparing Effects, Benefits, Uses, & Legality

The cannabis plant contains more than just THC and CBD—it’s also home to a variety of lesser-known cannabinoids with exciting potential. Two of the most promising are CBG (cannabigerol) and CBC (cannabichromene). While they don’t produce the “high” associated with THC, they interact with the body in unique ways that could support everything from focus to inflammation. Let’s explore the differences between CBG and CBC so you can make the most informed choice on your wellness journey.

What is CBG?

CBG, short for cannabigerol, is often called the “stem cell” or “parent” cannabinoid because it’s the compound from which other cannabinoids form. It’s found in smaller quantities than THC or CBD but has shown potential to interact with both CB1 and CB2 receptors. Early studies suggest CBG could support focus, digestion, and mood without intoxication (Cascio et al., 2010).

What is CBC?

CBC, or cannabichromene, is another non-psychoactive cannabinoid with anti-inflammatory and analgesic properties. Unlike CBG, CBC doesn’t bind strongly to cannabinoid receptors—instead, it interacts with TRPV1 and TRPA1 receptors, which are tied to pain and inflammation responses (DeLong et al., 2010). CBC may also play a role in neurogenesis and skin health.

CBG vs. CBC: Effects

CBG and CBC influence the body differently due to how they interact with various receptors.

Effects of CBG

• Mental clarity
• Gentle stimulation without euphoria
• Reduced inflammation, especially in the gut (Borrelli et al., 2013)

Effects of CBC

• Mild relaxation
• Anti-inflammatory support
• Subtle mood enhancement

CBG vs. CBC: Benefits

While more research is needed, early studies show that CBG and CBC may offer several health benefits.

Benefits of CBG

• Potential support for inflammatory bowel conditions (Borrelli et al., 2013)
• May assist with bladder control issues
• Neuroprotective properties in early models

Benefits of CBC

• May encourage new brain cell growth
• Possible pain relief without sedation (DeLong et al., 2010)
• Could reduce acne and skin inflammation when applied topically

CBG vs. CBC: Uses

While both cannabinoids are considered non-intoxicating, they are often used for different goals depending on the desired effect.

What is CBG Used For?

• Supporting attention and focus (Cascio et al., 2010)
• Easing digestive discomfort (Borrelli et al., 2013)
• Reducing inflammation in the gut and joints

What is CBC Used For?

• Promoting emotional balance
• Helping manage everyday aches (DeLong et al., 2010)
• Supporting skin clarity in topical formulations

CBG vs. CBC: Legality

The legal status of CBG and CBC depends on how they are sourced and the laws in your state.

Is CBG Legal?

CBG is federally legal if derived from hemp (containing less than 0.3% THC), but some states may regulate it differently.

Is CBC Legal?

Like CBG, CBC is typically legal when sourced from hemp, though local laws may impact availability.

Final Thoughts: Which Should You Choose?

Choosing between CBG and CBC depends on your wellness goals. If you’re looking for mental focus and digestive balance, CBG might be a great fit. For those more interested in mood support or skin benefits, CBC may be a better match. Trying them together may also enhance effects thanks to the entourage effect.

Using CBG and CBC Together

When CBG and CBC are combined, they may complement one another for a more balanced, full-spectrum experience. You’ll often find both included in broad-spectrum cannabis and hemp products for this reason.

Where to Find CBG and CBC Products

Ready to experience the power of minor cannabinoids? Zen Leaf offers a range of cannabis products featuring CBG, CBC, or blends of both. Visit a Zen Leaf dispensary near you or shop online for tinctures, edibles, and more.

Pro tip: Join Zen Leaf Rewards to earn points, unlock exclusive deals, and save more on the products that support your wellness.

References

• Borrelli, F., Fasolino, I., Romano, B., Capasso, R., Maiello, F., Coppola, D., ... & Izzo, A. A. (2013). Beneficial effect of the non-psychotropic plant cannabinoid cannabigerol on experimental inflammatory bowel disease. Biochemical Pharmacology, 85(9), 1306-1316.
• Cascio, M. G., Gauson, L. A., Stevenson, L. A., Ross, R. A., & Pertwee, R. G. (2010). Evidence that the plant cannabinoid cannabigerol is a highly potent alpha2-adrenoceptor agonist and moderately potent 5HT1A receptor antagonist. British Journal of Pharmacology, 159(1), 129-141.
• DeLong, G. T., Wolf, C. E., Poklis, A., Lichtman, A. H. (2010). Pharmacological evaluation of the natural constituent of Cannabis sativa, cannabichromene and its modulation by Delta9-tetrahydrocannabinol. Drug and Alcohol Dependence, 112(1-2), 126-133.